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Corey McMillan PhD

Co-Director, Associate Professor


The overall mission of Dr. Corey McMillan's Bioinformatics in Neurodegenerative Disease (BiND) Lab, housed within the Penn FTD Center, is to use multimodal and bioinformatic approaches to improve our understanding of the biological basis of neurodegenerative conditions. Corey McMillan's lab aims to develop robust biomarkers that can be used to better diagnose neurodegenerative diseases, accelerate drug discovery of disease-modifying agents, and to define essential clinical trial endpoint measures. His clinical-translation research program focuses on two classes of neurodegenerative proteinopathies including the misfolded tau protein that contributes to Alzheimer’s disease (AD), primary age-related tauopathy (PART), and frontotemporal lobar degeneration (FTLD), as well as the TDP-43 protein that contributes to a spectrum of FTLD and amyotrophic lateral sclerosis (ALS). His lab emphasizes biologically-grounded hypotheses with novel analytic and multimodal approaches integrating MRI and PET imaging modalities with genomics and clinical datasets. Corey is also affiliated with several research centers at the University of Pennsylvania including Penn Alzheimer’s Disease Research Center, Penn Institute on Aging, Penn Institute for Biomedical Informatics, Penn Neurodegeneration Genomics Center, and MindCORE.

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